This study provides proof-of-principle data for the use of trained immunity to modulate macrophage interactions with tumours. The study makes a valuable contribution to the field of trained immunity.

Adding immunotherapy to a new type of inhibitor that targets multiple forms of the cancer-causing gene mutation KRAS kept pancreatic cancer ... by bringing in more T cells and other immune cells ...

The process of α-cell to β-cell transdifferentiation requires tightly coordinated changes in several critical transcription factors. For the in vivo study, both db/db mice and pancreatic alpha cell ...

In contrast to established protocols for differentiating pluripotent stem cells into pancreatic alpha and beta cells, which report a fraction of delta cells as a by-product, our method significantly ...

Both the MRI and histology results point ... are commonly modified in tumor cell lines using capillary electrophoresis mass spectrometry (CE-MS) targeted metabolic profiling (Matsumoto et al., 2014).

Jef Akst was managing editor of The Scientist, where she started as an intern in 2009 after receiving a master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses.