Before arriving at Janelia three years ago, Postdoctoral Scientist Antonio Fiore was designing and building optical ...

Of course, external signals from neighboring cells or from the extracellular matrix are also important influences on the arrangement of cells in a tissue. Without cell division, long-term tissue ...

as well as between these cells and the extracellular matrix. These signaling pathways are critical to maintaining the state of equilibrium known as homeostasis within a tissue. For example ...

Scientists have developed Rhobo6, a light microscopy probe that reveals extracellular matrix structures in live tissues, advancing biological research and disease diagnostics. Rhobo6 is a light ...

New research has uncovered a complex interplay between extracellular matrix (ECM) structure and the transcriptional responses ...

Scientists find a way to predict which malignant tumours will become aggressive and metastasise to other parts of the body.

BENGALURU: Cells and spacing between them plays a crucial role for a healthy body. A team of researchers from the Indian ...

Laboratory for Research on the Structure of Matter (LRSM), University of Pennsylvania, Philadelphia, United States ...

Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

So far, Fiore's new direction is paying off. The extracellular matrix supports and gives structure to our cells and tissues: It provides a scaffold for cells to grow in, dictates the mechanical ...