As people age, a buildup of calcium on the aortic valve can make it thicker and stiffer leading to aortic stenosis. In addition, congenital heart defects, rheumatic fever, bacterial infections ...
The phase II data are promising for patients who are managed with watchful waiting before being offered an intervention.
Fibrosis predicts post-surgical risk in aortic stenosis, reinforcing its role in guiding treatment decisions for both sexes.
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