Open and endoscopic carpal-tunnel releases are commonly used as the definitive treatment for carpal tunnel syndrome. This ...

Patients with human epidermal growth factor receptor 2 (HER2)–positive early breast cancer with residual invasive disease after neoadjuvant systemic therapy have a high risk of recurrence and death.

This article describes the challenges and lessons learned in conducting a major public health campaign to connect immigrant ...

Key aspects of the Cedars-Sinai Community Connect Program, and its pilot program of targeted grantmaking, are the need to ...

A quantitative alcohol history should be recorded for all patients, because alcohol use contributes to many physical and mental disorders. A person-centered, nonjudgmental approach should be adopted.

Zoledronate prevents fractures in older women when administered every 12 to 18 months, but its effects on bone density and bone turnover persist beyond 5 years. Whether infrequent zoledronate ...

A majority of NEJM Catalyst Insights Council are comfortable and confident using virtual platforms to deliver care to ...

An urgent health care workforce crisis is looming. In the United States, a country plagued by disparate health outcomes across its geographic regions, relative physician “deserts” (i.e ...

Panel A summarizes the conventional model of how oncogenic RAS guanosine triphosphatases (i.e., Kirsten rat sarcoma viral oncogene homologue [KRAS], neuroblastoma RAS viral oncogene homologue ...

Drawing on organizational theory and their own semistructured interviews with C-suite leaders from 11 academic health systems ...

Beyond ensuring access to gender-affirming surgical care, U.S. carceral facilities can develop health care, housing, and security policies that recognize gender-affirming care as standard practice.

For over 200 years, the New England Journal of Medicine (NEJM) has brought important medical news to the world’s most influential physicians. The global medical community, physicians, and ...