researchers used a lentiviral vector to deliver gene therapy to five patients with hemophilia A. After treatment, all five had stable levels of factor VIII in their blood, with no serious safety ...

In the original lentivirus vectors described by Naldini et al (Naldini et al., 1996a) (Naldini et al., 1996b) , the vector pCMVΔR8.2 supplies all but the HIV envelope in trans, the vector pMD.G is ...

The majority are in the very early preclinical stage of development, but applications for regulatory approval have been ...

X-linked sideroblastic anemia (XLSA) is a rare genetic disorder caused by mutations in the ALAS2 gene, which plays a critical role in heme biosynthesis within red blood cells.

senior vice president of process and analytical development at viral vector manufacturer iVexSol, which uses its lentiviral vector technology to reduce the time and expense involved in cell and ...

Under the agreement, AGC Biologics will manufacture the lentiviral vector used to produce lete-cel, an engineered T-cell ...

Its multi-platform development approach applies the lentiviral vector and adeno-associated viral vector gene therapy platforms. Its clinical program is an LVV-based gene therapy for the treatment ...