The epithelial lining of our intestine is organized in a crypt-villi architecture and serves many essential functions including maintenance of barrier, digestion and nutrient absorption. Due to the ...

In vivo, the intestinal epithelium interacts with the neighboring environment through complex crosstalk, which involves components such as the immune system, tissue microenvironment, and gut microbes.

Epithelial apoptosis was measured in histopathological analysis, nuclear imaging, and terminal deoxynucleotidyl transferase dUTP nick end labeling. Plasma intestinal fatty acid-binding protein (I ...

Barrett's esophagus is an acquired metaplastic abnormality in which the normal stratified squamous epithelium lining of the esophagus is replaced by an intestinal-like columnar epithelium.

Intestinal stem cells are multipotent adult stem cells, which in mammals reside in the base of the crypts of the adult intestine. Intestinal stem cells continuously self-renew by dividing and ...

These proteins are essential for the organization and differentiation of intestinal epithelial tissue. Using this technique, the researchers were able to control how and where structures such as ...

Intestinal organoids that are classically grown in 3-D matrices are cystic, which means that they have a monolayer of epithelial cells with fluid inside. The cells interact with the matrix on the ...

The stem cells are propagated in vitro and form mature intestinal epithelium upon growth factor manipulation. In order to increase the complexity of this human biomimetic model, we are integrating ...